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Pathology JIPMER 2018 18932f00

Gross section of myoardium following myocardial infarction is shown. What could the duration following MI?

A
Immediate MI
B
2 days
C
2 weeks
D
Postmoem infarct aefact
High-Yield Explanation
C - This image shows Interventricular wall rupture. Rupture of myocardial tissue can occur in between 4 -7days Post- MI. (Usually 7-10 days) Commonest complication seen POST-MI is Arrhythmia. Specifically, Ventricular fibrillation. Time Post MI Gross Changes Microscopic Changes Clinical Complications < 4 Hours No observable changes No observable changes Arrhythmias, cardiogenic shock, congestive hea failure 4-24 Hours Dark discoloration Coagulative necrosis Arrhythmias 1-3 Days Yellow coloration Neutrophil invasion of infarct Fibrinous pericarditis 4-7 Days Yellow Coloration Macrophage invasion of infarct Rupture of ventricular wall leading to cardiac tamponade, interventricular septum leading to shunt, papillary muscle dysfunction leading to mitral insufficiency 1-3 Weeks Red border begins to form around infarct Granulation tissue with fibroblasts Months White Scar Fibrosis Aneurysm, mural thrombus, Dressler syndrome

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