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Anatomy Other topics and Adverse effects 18925c8a

Which of the following drugs inhibit 5'-deiodinase?

A
Propylthiouracil
B
Methimazole
C
Lugol's iodine
D
Radioactive iodine
High-Yield Explanation
(Ref: KDT 6/e p249, 250) For the peripheral conversion of T4 to T3 the enzyme needed is 5'-deiodinase. It is inhibited by Propylthiouacil, Propanolol, Amiodarone.

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