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Pharmacology Miscellaneous (Pharmacology) 188d3826

Drug that does not follow nonlinear dose dependent saturation kinetics

A
Paracetamol
B
Salicylates
C
Phenytoin
D
Ethanol
High-Yield Explanation
(A) Paracetamol # Nonlinear Pharmacokinetics> Nonlinearity in pharmacokinetics (i.e., changes in such parameters as clearance, volume of distribution, and half-life as a function of dose or concentration of drug) usually is due to saturation of either protein binding, hepatic metabolism, or active renal transport of the drug.

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