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Pharmacology All India exam 18793fdf

About Ramelteon, which of the following is not true?

A
MT1 and MT2 receptor antagonist
B
Metabolized by Cytochrome p450
C
No significant addictive potential
D
Useful in long-term treatment of insomnia
High-Yield Explanation
Ramelteon is melatonin receptor agonist, rapidly absorbed and undergoes extensive first-pass metabolism. Ramelteon is a melatonin receptor agonist with both high affinity for melatonin MT1 and MT2 receptors and selec vity over the MT3 receptor.

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