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Microbiology General 180fe749

A patient presents with lower gastrointestinal bleed. Sigmoidoscopy shows ulcer in the sigmoid. Biopsy from this area shows flask-shaped ulcers. Which of the following is the most appropriate treatment ?

A
Intravenous ceftriaxone
B
Intravenous metronidazole
C
Intravenous steroids and sulphasalazine
D
Hydrocoisone enemas
High-Yield Explanation
Ans. is 'b' i.e., Intravenous metronidazole Flask-shaped ulcer in a patient of GI bleed suggests amebiasis (amoebic dysentry). Drug therapy for amoebiasis Asymptomatic carrier --> Luminal agents (Iodoquinol, Paromomycine) Diloxanide furoate is the DOC. Acute colitis --> Metronidazole or Tinidazole + Luminal agent. Liver abscess Metronidazol or Tinidazole or ornidazole + Luminal agent.

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