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Medicine General 180ca2cb

Inherited Metabolic Neurological Syndrome associated with acanthocytosis is:

A
Abetalipoprotenemia
B
Wolman Syndrome
C
Mc Leod Syndrome
D
All of the above
High-Yield Explanation
Answer is D (All of the above): Several neurological Syndromes are associated with abnormal erythrocytes called acanthocytes characterized by spiny projections from their cell surface. (Acantho' is derived from a Greek word meaning 'thorns). The most impoant of these are Abetalipoproteinemia ((Bassen-Kornzweig Disease), Choreo-acanthocytosis (Levine-Critchley Syndrome; Neuroacanthocytosis) and McLeod Syndrome. Neurological Syndromes with Acanthocytosis Abetalipoproteinemia ((Bassen-Kornzweig Disease) Choreo-acanthocytosis (Levine-Critchley Syndrome; Neuroacanthocytosis) McLeod Syndrome Wolman Syndrome (Neurological involvement is generally mild)

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