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Pediatrics Musculoskeletal disorders 176f6913

Which of the following is false about Duchenne muscular dystrophy?

A
Duchenne muscular dystrophy is less severe than Becker's dystrophy
B
X-linked recessive
C
Dilated cardiomyopathy is seen
D
Intellectual impairement is common
High-Yield Explanation
Duchenne muscular dystrophy is more severe than Becker&;s dystrophy. Becker&;s dystrophy is similar to Duchenne muscular dystrophy with a genetic defect at the same locus (Xp21) but clinically less severe. Impoant differences between Duchenne and Becker&;s muscular dystrophy: Duchenne&;s dystrophy Becker&;s dystrophy Onset Age: 2-3 years Age: 5-15 years Weakness Progressive Variable Intellectual impairement Common Uncommon Prognosis Wheel chair dependent bby adolescence Ambulatory till early adult life Death By the age of 18-20 years By the age of 40-50 years Ref: Nelson textbook of pediatrics 21st edition Pgno: 3281

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