Which of the following is false about Duchenne muscular dystrophy?
High-Yield Explanation
Duchenne muscular dystrophy is more severe than Becker&;s dystrophy. Becker&;s dystrophy is similar to Duchenne muscular dystrophy with a genetic defect at the same locus (Xp21) but clinically less severe. Impoant differences between Duchenne and Becker&;s muscular dystrophy: Duchenne&;s dystrophy Becker&;s dystrophy Onset Age: 2-3 years Age: 5-15 years Weakness Progressive Variable Intellectual impairement Common Uncommon Prognosis Wheel chair dependent bby adolescence Ambulatory till early adult life Death By the age of 18-20 years By the age of 40-50 years Ref: Nelson textbook of pediatrics 21st edition Pgno: 3281