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Microbiology Bacteria 170fd256

Streptococcal Toxic shock syndrome is due to the following virulence factor :

A
M protein
B
Pyrogenic exotoxin
C
Streptolysin O.
D
Carbohydrate cell wall.
High-Yield Explanation
Ans. is 'b' i.e. Pyrogenic exotoxin Streptococcal toxic shock syndrome is caused due to the release of pyrogenic exotoxins or erythrogenic exotoxins. * These exotoxins are produced only by few strains of beta hemolytic group A streptococci. *Usually these toxins cause scarlet fever but sometimes these strains produce exotoxins that are superantigens.These superantigens (exotoxins) directly super stimulate T cells to pour out inflammatory cytokines. This causes streptococcal toxic shock syndromeMore questions on erythrogenic or pyrogenic exotoxinsDick testIt is a test used to identify children susceptible to scarlet fever.Intradermal injection of erythrogenic toxin into susceptible individual produces an erythematous reaction.Schultz Charlton reactionIt is a diagnostic test for scarlet fever.Blanching of the rash produced during scarlet fever on local injection of convalescent serum is called Schultz Charlton reaction.Also know:

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