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Pathology Miscellaneous (Kidney) 170728d2

Chromosome for RCC is -

A
3
B
X
C
22
D
20
High-Yield Explanation
Ans. is 'a' i.e., 3 o Clear cell carcinoma is the most common renal cell carcinoma and is associated with 3p deletion.Chromosomal abnormalities associated with RCCClear cell carcinomaDeletion of short arm of chromosome-3 (3p deletion), i.e. VHL gene.Papillary CarcinomaSporadic : Trisomy of 7, 16, 17; loss of Y chromosome (Y); t (X: 1). Hereditary: Trisomy 7.Chromophobe (oncocytic) renal cell carcinomaHypodiploidy or monosomy due loss of multiple chromosomes: 1, 2, 6, 10, 13,17, 21, & Y

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