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Pharmacology Endocrinology 17040da4

If a diabetic patient being treated with an oral hypoglycemic agent develops dilutional Hyponatremia, which one of the following could be responsible for this effect

A
Chlorpropamide
B
Tolbutamide
C
Glyburide
D
Glimepride
High-Yield Explanation
Refer KDT 6 /e p 267 Chlorpropamide is a first generation Sulfonylureas It increases the risk of hypoglycemia Other adverse effects of Chlorpropamide are ADH like action leading to dilutional Hyponatremia Cholestatic jaundice Disulfuram like reaction

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