Two most important clinical features of primary biliary cirrhosisa) Generalized pruritusb) Jaundicec) Fatigued) Clubbinge) Hematemesis

• MC indication for LT: Cirrhosis from Hepatitis C (HCV) • 2nd MC indication for LT: Alcoholic liver disease • MC indication for LT in children: Biliary atresia • MC metabolic disorder requiring LT: Alpha-1 antitrypsin deficiency • MC indication for LT following acute liver failure: Acetaminophen toxicity • Sepsis and sepsis-induced multiple organ failure are the MC causes of death in liver transplantation.