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Pharmacology General 16be15b4

The diuretic group that does not require access to the tubular lumen to induce diuresis is ?

A
Carbonic anhydrase inhibitor
B
Na-Cl sympo inhibitor
C
Mineralocoicoid antagonist
D
Na-K sympo inhibitor
High-Yield Explanation
Ans. is 'c' i.e. Mineralocoicoid antagonist Spirinolactone is mineralocoicoid (aldosterone) antagonist. It opposes the action of Aldosterone without requiring access to the tubular lumen. Spirinolactone (as well as aldosterone) act from the interstitial side.

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