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Physiology Blood: Hemostasis and Blood Coagulation 161b173a

Common step in coagulation pathway is -

A
Activation of factor VII
B
Activation of factor VIII
C
Activation of factor IX
D
Activation of factor X
High-Yield Explanation
Ans. is 'd' i.e., Activation of factor X o Blood coagulation pathways are divided into:-i) Intrinsic pathway (contact pathway) : It is largely an 'in vitro9 pathway and is activated when factor XII (Hageman factor or contact factor) comes in contact with negatively charged surface, e.g. glass, kaolin etc.ii) Extrinsic pathway : It is largely an in vivo pathway is activated by tissue factor (thromboplastin) at the site of tissue injury.

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