Orthopaedics Osteochondritis and Avascular Necrosis 16152ced

Which of the following statements about changes in aicular cailage with ageing is not true:

Total proteoglycan content is decreased

Synthesis of proteogycans is decreased

Enzymatic degradation of proteoglycans is increased

Total water content of cailage is decreased

High-Yield Explanation

Cailage propey Aging Osteoahritis Hydration Decreased Increased ( in late OA its also decreased) Proteolytic enzymes Normal Increased Proteoglycan content Decreased(due to decreased synthesis) Decreased (due to increased destruction)

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Which of the following statements about changes in aicular cailage with ageing is not true:

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