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Biochemistry Vitamins and Minerals 1604a434

In Non competitive inhibition of enzyme:

A
Decreased Km, increase Vmax
B
Increase Km, Increase Vmax
C
Normal Km, decrease Vmax
D
Normal Km, increase Vmax
High-Yield Explanation
Ans. (c) Normal Km, decrease VmaxRef: Harper's Biochemistry, 30th edn. pg. 81-82Type of InhibitionKmVmaxCompetitive inhibitionINCREASEDSAMENon- Competitive inhibitionSameDECREASEDCompetitive Inhibition: Substrate and inhibitor Both compete for same site on enzyme.Non-Competitive Inhibition: Substrate and Inhibitor both bind at different site in the enzyme.

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