A 20 yr old uncontrolled diabetic presents with sinus swelling and black necrotic mass in the nasal cavity is mostly due to which organism?
High-Yield Explanation
Ans. is 'a' i.e., Mucormycosis Mucormycosis* Mucormycosis is fungal infection of nose and paranasal sinuses, which may prove rapidly fatal if untreated.* It is seen in uncontrolled diabetics or in those taking immunosuppressive drugs.* It presents as black necrotic mass filling the nasal cavity and eroding the septum and hard palate.* From the nose and sinuses, infection can spread to orbit, cribriform plate, meninges and brain.* The rapid destruction associated with the disease is due to affinity of fungus to invade the arteries and cause endothelial damage and thrombus.* Treatment is by amphotericin B and surgical debridement.