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Pediatrics Central Nervous System 1558e0ee

Treatment of infantile spasm includes all except-

A
Corticosteroids
B
Phenytoin
C
ACTH
D
Vigabatrin
High-Yield Explanation
Ans. is 'b' i.e., Phenytoin Infantile spasm (Infantile myoclonus or West syndrome)* The onset is usually between 3-8 months of life* It is characterized by triad of -i) Salaam spells (sudden dr oping of the head & flexion of arms)ii) Mental retardationiii) Hypsarrhythmic pattern ofEEG (diffuse high voltage slow spike and chaotic activity)* The spasm occur in clusters usually on waking.* Prognosis for normal mental development is poor.* Vigabatrin (drug of choice), ACTH (2nd choice) and corticosteroids are used for treatment.

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