Breast conservative surgery is done in all except:-

Breast Conservation Surgery (BCS)- Performed for early invasive breast cancer (Stage I, IIA, IIB)Treatment options- Excision of lump - Lumpectomy- Wide local excision with 1 cm margin- Whole quadrant excision (Quadrantectomy) Lobular carcinoma is frequently multifocal, multicentric and bilateral and is contraindication for breast conservative surgery. Contraindications of Breast conservation surgery Absolute contraindications Relative contraindications Pregnancy H/ O Collagen vascular disease (Scleroderma, Active lupus erythematosus) 2 or >2 tumors in different quadrants or diffuse malignant appearing diffuse micro-calcification. Multiple tumors in same quadrant Persistently +ve margins Large tumor in small breast History of exposure of therapeutic radiation Large pendulous breast (difficult to give uniform dose of radiotherapy) Centrally located tumor (excision of nipple and areola should also be done for centrally located tumor but reconstruction of nipple of areola is difficult