4-year-old male child had febrile seizures, best prophylaxis –
High-Yield Explanation
Prophylaxis in febrile seizures
Prophylactic anticonvulsants are not given routinely in febrile seizures. They are required when -
A febrile seizure is prolonged or complicated
Medical reassurance fails to relieve family anxiety.
Prophylaxis may be continuous or intermittent
Intermittent prophylaxis
It is currently the desirable form of therapy
It is used during episodes of fever
Indicated during first three days of fever:
Drugs that are used are - Diazepam and other benzodiazepines (these drugs are used because they attain desired levels quickly) Diazepam is given oral or rectal.
Continuous prophylaxis -
It is used when
Intermittent therapy has failed
Central nervous system disease
Drugs used are → Sodium valproate or phenobarbitone.
Recurrent atypical seizures
The family history of epilepsy
Note - Carbamazepine and phenytoin are ineffective for prevention of recurrence.