Full 2L QBank
Biochemistry Urea cycle 143d959a

In all of the following enzyme deficiencies, hyperammonemia is a common feature, EXCEPT:

A
Argininosuccinate synthetase
B
Carbamoyl Phosphate synthetase (CPS-I)
C
Ornithine transcarbamoylase (OTC)
D
Ornithine amino transferase
High-Yield Explanation
Excess ornithine from urea cycle is taken by enzyme OAT (Ornithine amino transferase) OAT deficiency leads to gyrate atrophy. In this deficiency, plasma, urine, spinal fluid and aqueous humour concentration of ornithine levels are 10-20 times higher than normal Hyperammonemia is absent because urea cycle is not disrupted in this deficiency Hyperammonemia occurs in enzyme deficiency of Urea cycle

Related Biochemistry MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now