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Pediatrics Endocrinology 1403da8b

Sexual ambiguity may be seen in which of the following conditions ?

A
Androgen insensitivity
B
Pure gonadal dysgenesis
C
Sawyer syndrome
D
Mixed gonadal dysgenesis
High-Yield Explanation
Genital assymetry is mostly due to mixed gonadal dysgenesis,ovotesticular disorders of sexual differentiation. Figure : Phenotypic characteristics of external and internal genitalia at bih. (A) Eighty-five percent of the patients had a hemiscrotum containing a gonad on one side and hemi-labia on the other side. All patients had a unique orifice (arrow). (B) Vaginal pocket (arrow): 92% of the patients had a hemiuterus (asterisk). Reference: OP Ghai ,essential paediatrics ,8th edition. page no 539 ,table 17.33

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