Increased Reid Index is used to characterized:
High-Yield Explanation
Answer is A (Chronic Bronchitis): Reid Index is a measure of hyperophy of the mucus secreting glands and is characteristically increased in Chronic Bronchitis. Reid Index: Measures Hyperophy of mucus glands Chronic Bronchitis is assoicated with hyperophy of the mucus secreting glands of the submucusa in the cailaginous airways. The histologic correlate of chronic bronchitis is the presence of mucus gland hyperplasia. This manifests as an increased percentage of bronchial wall occupied by submucosal mucus glands (This is classically defined by the 'Reid Index'.) Reid Index is the ratio of the thickness of the mucous gland layer to the thickness of the bronchial wall (between basal lamina of mucosa and inner perichondrium) The normal Reid Index is less than 0.4 Reid index > 0.4 (typically > 0.5) suggests mucous gland hyperplasia The Reid index is increased in chronic bronchitis usually in propoion to the severity and duration of disease. There is a direct correlation between the value of Reid Index and the volume of daily sputum production by the patient.