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Physiology Pituitary 13a3f5c7

In diseases of growth hormone cell death occurs by-

A
Aging
B
Apoptosis
C
Necrosis
D
All of the above
High-Yield Explanation
Ans. is 'b' i.e., Apoptosis o GH and IGF-1 (somatomedin) inhibit cell death by apoptosiso Thus, GH deficiency will cause accelerated apoptosis."GH indirectly mediates growth and protein synthesis by triggering the liver and other tissues to produce a group of proteins called insulin-like growth factors (IGFs). These proteins enahnce cellular proliferation and inhibit apoptosis or programmed cell death " -- Science in medicine.

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