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Pharmacology General Pharmacology 12eec0e4

The mitochondrial enzyme involved in the metabolism of clopidorgel and proton pump inhibitors is:

A
CYP 2A
B
CYP 2B
C
CYP 2C19
D
CYP 2D6
High-Yield Explanation
Ans. (C) CYP 2C19(Ref: Katzung 13th/e p80)Clopidogrel and proton pump inhibitors are metabolized mainly by CYP2C19 and by CYP3A4. Due to this reason there is potential of interaction between these two drugs

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