Which among the following carcinoma is treated by radiotherapy?
High-Yield Explanation
Over 95% of endemic nasopharyngeal carcinomas (NPC) are classified as WHO type 3 and associated with EBV. NPC tends to occur in younger persons and is not associated with tobacco usage. NPC is an aggressive neoplasm with cervical lymph node metastases present in 60 to 90% of patients at diagnosis. Because of unique anatomic, biological, and clinical characteristics, therapy for NPC is distinctive. Radiotherapy is the mainstay of local therapy. NPCs are highly chemoradiosensitive. Intensity-modulated radiation therapy (IM) allows for greater conformality of the high-dose regions with relative sparing of adjacent normal tissues compared to traditional radiation techniques.