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Gynaecology & Obstetrics Antenatal Screening 12a58456

A mother with 10 wks pregnancy and who had previously baby with open neural tube defect which statement is true -

A
Sodium valproate causes open neural tube defect.
B
Risk of recurrence is 10%
C
Aminocentesis should be done
D
Give multivitamin.
High-Yield Explanation
Ans. is 'a' i.e. Sodium valproate causes open neural tube defect.Sodium valproate causes neural tube defect when given to pregnant ladies.Folic acid supplementation is given to prevent neural tube defect (not multivitamins).Risk of recurrence of neural tube defect is 5%* (not 10%).Amniocentesis is used to diagnose neural tube defects but the ideal time is 14-16 wks*.

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