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Pediatrics General 1226067c

In shigella dysentry associated hemolytic uremic syndrome, the false statement is ?

A
Leucocytosis
B
Neurological abnormalities
C
Hepatic failure
D
Thrombotic angiopathy
High-Yield Explanation
Ans. is 'c' i.e., Hepatic failure o Hepatic failure does not occur in HUS. Laboratory findings of HUS o Thrombocytopenia o Leukocytosis o ARF r BUN and creatinine with oliguria o Microscopic hematuria o Peripheral smear Helmet cells, burr cells, fragmental RBCs (Schistocytes). o Proteinuria o Hemoglobinuria with hemosiderinuria o Normal PT and APTT Option 'b' requires some explanation here ? Though neurological manifestations may occur in HUS, these are not common and this feature differentiated HUS from TTP. In TTP neurological symptom is one of the clinical criteria for diagnosis.

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