Longest acting drug among the following drugs for over reactive bladder:

Solefenacin is the longest acting drug from this group. Gastro-intestinal tract Anticholinergic drugs decrease the motility, tone and secretions in the gastrointestinal tract. — Pirenzepine and telenzepine are selective M1 blockers useful in peptic ulcer disease. — Hyoscine, dicyclomine, propantheline, oxyphenonium and clidinium are useful as anti-spasmodic agents for the treatment of intestinal colic. — Darifenacin and solefenacin are selective M3 blockers useful for irritable bowel syndrome and overactive bladder. Oxybutynin is shortest acting and solefenacin is longest acting drug from this group. Mirabegron is a newer drug approved for overactive bladder. It acts by stimulating β3 receptors.