DOC for Iepra II reaction is
High-Yield Explanation
Type 1 reaction Type 2 reaction Pathology T cell mediated type 4 hypersensitivity reaction Immune complex mediated type 3 hypersensitivity reaction Clinical features Erythema Edema of preexisting lesions, neuritis Evanescent erythematosus nodules with ahritis, myalgia fever, constitutionalists symptoms Systemic involvement - Characterised by neuritis, orchitis, hepatitis, nephritis, ahritis, iritis, Drug of choice Mild reaction rest and analgesics moderate to severe reaction: coicosteroids are the drug of choice Mild reaction: rest , chloroquine moderate to severe reaction drug of choice thalidomide