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Anaesthesia General 11d019a4

Site of action of epidural analgesia

A
Sensory nerve endings
B
Ventral horn
C
Substantia gelatinosa
D
Coex
High-Yield Explanation
C i.e. Substantia gelatinosa Opoid receptors are maximum in Lamina 2 (substantia gelatinosa) Lamina 5 of spinal cord. So Epidural Narcotics acts mainly on substantia gelatinosa Common side effects of intraspinal/ epidural opioids are pruritis (itching), nausea - vomiting; urinary retention, sedation, ileus and dose dependent respiratory depression (most serious)Q

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