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Microbiology Immunology 11967b79

The secretory component of immunoglobulin molecule is -

A
Formed by epithelial cells of lining mucosa
B
Formed by plasma cell
C
Formed by epithelial cell and plasma cell
D
Secreted by bone marrow
High-Yield Explanation
The secretory component is a component of immunoglobulin A (IgA). Secretory component is a proteolytic cleavage product of the polymeric immunoglobulin receptor which remains associated with dimeric IgA in sero-mucus secretions. Polymeric IgA binds to the polymeric immunoglobulin receptor on the basolateral surface of epithelial cells and is taken up into the cell transcytosis. Ref: Ananthanarayan & Panikers textbook of microbiology 9th edition pg:97

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