Full 2L QBank
General Medicine General 115e3890

An 8-year-old child is evaluated by the pediatrician, who notes small cafe-au-lait spots on the child's torso. In addition, on close inspection of the eyes, the presence of Lisch nodules is noted. The patient is eventually diagnosed with neurofibromatosis type 1. The protein that is mutated in this disorder normally does which of the following functions?

A
Activates the GTPase activity of Ras
B
Cleaves cellular proteins during apoptosis
C
Functions as a cell cycle checkpoint regulator
D
Promotes angiogenesis

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