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Biochemistry All India exam 111cb9f6

With help of the drug shown below, serotonin is synthesized from which of the following precursor amino acid?

A
Tryptophan
B
Glycine
C
Threonine
D
Methionine
High-Yield Explanation
Tryptophan. Serotonin is synthesized from the essential amino acid tryptophan. The rate-limiting step is the conversion of the amino acid to 5-hydroxytrptophan by tryptophan hydroxylase. This is then conveed to serotonin by the aromatic L-amino acid decarboxylase which needs Pyridoxal Phosphate as a cofactor Ref : vasudevan 7th ed

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