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Unknown General 110f1f3b

Which statement regarding transmission of viral illness through homologous blood transfusion is true?

A
The most common viral agent transmitted via blood transfusion is HIV
B
Blood is routinely tested for CMV because CMV infection is often fatal
C
The most frequent infectious complication of blood transfusion continues to be viral meningitis
D
Up to 10% of those who develop post transfusion hepatitis will develop cirrhosis or hepatoma or both.
High-Yield Explanation
CMV is harbored in blood leukocytes. While acute CMV infection may cause transient fever, jaundice, and hepatosplenomegaly in cases of large blood donor exposures, post transfusion l.CMV infection (seroconversion) is not a significant clinical problem in immunocompetent recipients, and therefore blood is not routinely tested for the presence of CMV Post transfusion non-A, non-S hepatitis, however, not only represents the most frequent infectious complication of transfusion but also is associated with an incidence of chronic active hepatitis up to 16% and an 8 to 10% incidence of cirrhosis or hepatoma or both. The etiologic agent in over 90% of cases of post transfusion hepatitis has' been identified as hepatitis C.

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