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Pharmacology General 1092cd22

Inhibition of 5-lipoxygenase is useful in -

A
Cardiac failure
B
Bronchial asthma
C
Hepatic failure
D
Ahritis
High-Yield Explanation
Ans. is 'b' i.e., Bronchial Asthma Lipoxygenase acts on Arachidonic acid to release leukotrienes which are impoant inflammatory mediators. They are respnsible for the bronchospasm during asthma attack. o So as obvious any drug which inhibits 5 lipoxygenase will prevent the formation of Leukotrienes and will be useful in the tit of Asthma.

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