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Pathology G.I.T. 1071b9df

Gene associated with familial adenomatous polyposis is?

A
p53
B
Rb
C
APC
D
RET
High-Yield Explanation
Ans. is 'c' i.e., APC * Li-Fraumeni syndrome is due to germ line mutation in p-53 gene.SyndromeGeneChromosome* Familial adenomatous polyposis* APC* 5q21* Familial Wilms tumor* WTl* 11p13* Hereditary breasti ovarian cancer* BRCA1* BRCA2* 17q21* 13q12.3* Hereditary retinoblastoma* RBI* 13q14.2* Multiple endocrine neoplasia type 1* MENl* 1lq13* Multiple endocrine neoplasia type 2a* RET* 10q11.2* Neurofibromatosis type 1* NFl* 17q11.2* Neurofibromatosis type 2* NF2* 22q12.2* Li-fraumeni syndrome* p53* 17* Melanoma* p16INK4A

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