Pharmacology G.I.T 10436a01

Mechanism of action of metoclopramide:

Increase the lower esophageal sphincter

Decrease the acid secretion

Increase gastric peristalsis

Ulcer healing agent

High-Yield Explanation

Ans. A. Increase the lower esophageal sphincterMetoclopramide is prokinetic drug. It acts on D2 and 5Ht3 receptor. There is increase in acetylcholine level and there is increase in LES and gastric motility.

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Mechanism of action of metoclopramide:

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