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Pharmacology General 101b2a04

Rapid termination of the action of Suxamethonium is due to -

A
Rapid renal elimination
B
Enzymatic degradation by pseudocholinesterase
C
Metabolized by liver to acetyl CoA
D
Redistribution
High-Yield Explanation
Ans. is 'b' i.e., Enzymatic degradation by pseudocholinesterase o SCh is rapidly hydrolysed by plasma cholinersterase, some patients have genetically determined abnormality or deficiency of pseudocholinesterase, in them, SCh causes phase II block (dual block).

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