Clozapine was the first antipsychotic drug. Which of the following is an indication for the use of Clozapine?
High-Yield Explanation
Clozapine has been approved for, Patients with schizophrenia who have failed to respond adequately to typical neuroleptic drugs (treatment-resistant schizophrenia) Patients who are intolerant of typical neuroleptic drugs because of EPS or tardive dyskinesia Patients who are at high risk for suicide Ref: Meltzer H.Y., Bobo W.V., Heckers S.H., Fatemi H.S. (2008). Chapter 16. Schizophrenia. In M.H. Ebe, P.T. Loosen, B. Nurcombe, J.F. Leckman (Eds),CURRENT Diagnosis & Treatment: Psychiatry, 2e.