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Pharmacology Other topics and Adverse effects 0fffad43

Psoralen-A is used in the treatment of:

A
Pemphigus
B
Vitiligo
C
Pityriasis alba
D
Icthyosis
High-Yield Explanation
Photochemotherapy (PUVA: Psoralen ultraviolet A)- Photoactivated psoralen undergoes 02 independent as well as 02 dependent reactions and binds to pyrimidine bases- interferes with DNA synthesis and epithelial cell turnover. Oral methoxsalen is followed 1-2 hours later by UVA exposure on alternate days. ESSENTIALS of medical PHARMACOLOGY SEVENTH EDITION-KD TRIPATHI page:892

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