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Anaesthesia General 0ffbd000

Which of the following inhalational agents has the minimum blood gas solubility coefficient ?

A
Isoflurane
B
Sevoflurane
C
Desflurane
D
Nitrous oxide
High-Yield Explanation
Desflurane has minimum blood : gas partition coefficient (minimum blood solubility) → fastest onset and recovery amongst inhalational anaesthetic agents. Speed of onset & recovery in decreasing order (Increasing order of B : G partition coefficient & blood solubility) :- Desflurane (0.42) > cyclopropane (0.44) > N2O (0.47) > Sevoflurane (0.69) > Isoflurane (1.38) > Enflurane (1.8) > Halothane (2.4) > Chloroform (8) > Trilene (9) > Ether (12) > Methoxyflurane (15). Diffusion coefficient also will be in the same decreasing order → desflurane has minimum diffusion coefficient and methoxyflurane has maximum diffusion coefficient.

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