Indication for cryoprecipitate is

Medical uses for giving cryoprecipitate include: Haemophilia - Used for emergency back up when factor concentrates are not available. von Willebrand disease - Not currently recommended unless the last reserve. ddAVP is the first line, followed by factor concentrates. Hypofibrinogenaemia (low fibrinogen levels), as can occur with massive transfusions Afibrinogenemia Bleeding from excessive anticoagulation - Fresh frozen plasma contains most of the coagulation factors and is an alternative choice when anticoagulation has to be reversed quickly. Massive hemorrhage - RBCs and volume expanders are preferred therapies. Disseminated intravascular coagulation Uremic bleeding tendency