In agranuloma , epthiloid cells and giant cells are derived from

ref Robbins 9/e p97 All granulomas, regardless of cause, may contain additional cells and matrix. These include lymphocytes, neutrophils, eosinophils, multinucleated giant cells, fibroblasts and collagen (fibrosis). The additional cells are sometimes a clue to the cause of thegranuloma. Macrophage and monocytes are also present