Anti-CD 25 monoclonal antibody used in prophylaxis of acute organ rejection in adult patients is

Ref. KDT. Page. 871-72 Basiliximab exhibits high affinity towards IL-2 receptor, inhibiting it. Anti- CD-25 antibody High affinity for IL-2 receptor Short plasma half life - 1 week Useful in preventing transplant rejection reactions. Adverse effects - Anaphylactic reactions & opportunistic infections.   Muromonab - CD3 is an immunosuppressant drug given to reduce acute rejection in patients with organ transplant Efalizumab - It is a monoclonal antibody that binds to CD11a, a cellsurface protein that has a key role in the pathological immune response in the skin disorder psoriasis. Eculizumab – used in treatment of PNH