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Pathology Blood 0f1fbca0

NOT true regarding Iron metabolism

A
Ascorbic acid promotes absorption
B
Absorption takes place in the terminal ileum
C
Phytates inhibit absorption
D
Most of iron is incorporated into red blood cells
High-Yield Explanation
(Absorption takes place in the terminal ileum): ( /edition)* Iron is mainly absorbed in the stomach and duodenum* In normal people about 10% of dietary iron is usually absorbed* Ferrous form is soluble and readily absorbedFactors affecting Fe absorption (414-15. U. Satycmarayan 4th)1. Acidity, ascorbic acid, alcohol fructose and cysteine promotes iron absorption2. In iron deficiency anemia, Fe absorption is increased to 2-10 tims that of normal3. Small peptides and amino acids favour iron uptake4. Phytate (found in cereals) and oxalate (found in leafy vegetables) interfere with Fe absorption5. A diet with high phosphate content decreases Fe absorption while low phosphate promotes6. Impaired absorption of iron is absorbed in malabsorption of stomach and/or intestine, iron absorption is severely impaired* Normally the loss of iron from the body of a man is limited to 1 mg per day

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