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Pathology Respiratory system 0f0c6fcb

Which paraneoplastic syndrome is not seen with small cell ca lung -

A
PTI
B
ACTH
C
ADH
D
Carcinoid syndrome
High-Yield Explanation
Ref:Textbook of pathology (Harsh mohan) 6th edition,page no.502 Paraneoplastic syndromes. A number of paraneoplastic syndromes are associated with lung cancer. These include the following: i) Ectopic hormone production: Different hormonal syndromes are characteristic of different histologic types of lung cancer. Small cell carcinomas are associated most often with ectopic hormone production. The various hormones elaborated by lung cancer are as follows: a) ACTH, producing Cushing's syndrome. b) ADH, inducing hyponatraemia. c) Parathormone, causing hypercalcaemia. d) Calcitonin, producing hypocalcaemia. e) Gonadotropins, causing gynaecomastia. f) Serotonin, associated with carcinoid syndrome.

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