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Pharmacology General 0eef2226

All of the following drugs cause pancreatitis as side effect, EXCEPT:

A
Captopril
B
Furosemide
C
Valproic acid
D
Didanosine
High-Yield Explanation
Adverse effects of captopril are -hypotension -acute renal failure in patients with bilateral renal aery stenosis -hyperkalemia -dry cough and -angioedema. Drugs associated with highest incidence of pancreatitis are didanosine, sodium valproate, 5 aminosalicylates and oestrogens. Drugs causing pancreatitis: Didanosine Furosemide and thiazide diuretics Mesalazine Metronidazole Oestrogens Pentamidine Sodium valproate Sulfasalazine Sulfonamides Tetracycline Ref: Adverse Drug Reactions edited by Anne Lee page 183. Benowitz N.L. (2012). Chapter 11. Antihypeensive Agents. In B.G. Katzung, S.B. Masters, A.J. Trevor (Eds), Basic & Clinical Pharmacology, 12e.

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