Which among the following is TRUE regarding transpo of substances through the cell membrane, EXCEPT:
High-Yield Explanation
Facilitated diffusion is a form of transpoer-mediated membrane transpo that does not require energy input. Just as in passive diffusion, the transpo of ionized and non-ionized compounds across the plasma membrane occurs down their electrochemical potential gradient. Therefore, steady state will be achieved when the electrochemical potentials of the compound on both sides of the membrane become equal. Active transpo is the form of membrane transpo that requires the input of energy. It is the transpo of solutes against their electrochemical gradients, leading to the concentration of solutes on one side of the plasma membrane and the creation of potential energy in the electrochemical gradient formed. Ref: Giacomini K.M., Sugiyama Y. (2011). Chapter 5. Membrane Transpoers and Drug Response. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.