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Medicine General 0ea904f1

All of the following statements are true about Hemolytic uramic syndrome except-

A
Uraemia
B
Hypofibhrinogenemia
C
Thrombocytopenia
D
Positive coomb's test
High-Yield Explanation
Answer is D (Positive Coomb's test) Comb's test is characteristically negative in patients with HUS. Hemolytic Uremic Syndrome is characterised by a microangiopathic hemolytic anemia, and thrombocvtopenia. The LDH is usually elevated out of propoion to degree of hemolvsis, and the coomb's test is negative. Coagulation test are normal with the exception of elevated fibrin degradation products (7 (explains hypofibrinogenemia) - normal coagulation results exclude DIC. Remember the following essentials of diagnosis : 1. Microangiopathic hemolytic anemia (coomb's negative).Q 2. Thrombocytopenia Q 3. Renal failureQ 4. Elevated LDHQ 5. Normal coagulation tests (exclude D1C)Q (an exception is elevated FDP) Q

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