Hemophilia A has following except -
High-Yield Explanation
Hemophila A
Hemophilia A is due to deficiency of factor VIII.
Hemophilia A is inherited as an X-linked recessive trait.
Factor VIII is an intrinsic pathway component required for activation of factor X.
Clinical manifestations are due to defect in coagulation system : -
Large post-traumatic ecchymoses or hematoma.
Prolonged bleeding after a laceration or any form of surgical procedure.
Bleeding into weight-bearing joints.
Petechiae are characteristically absent (in contrast to platelet dysfunction where bleeding occurs from small vessels of the skin and mucous membrane, e.g., petechiae).
Laboratory findings
↑ PTT
Normal PT
Normal BT
Normal platelet counts
Remember
Hemophilia B (Christmas disease) is due to deficiency of factor IX.
Hemophilia B has clinical features and laboratory findings similar to hemophilia A.